hypoglycemia

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

---

Study Counts

Type	Study_count
Total_Studies	345
interventional	283
Observational	61
Registry	1

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type	Study_Count
Drug	58
Device	54
Drug|placebo	43
Other	43
Behavioral	16
Drug|Other	12
Dietary Supplement	10
Procedure	10
Device|Drug	7
Biological	3
Dietary Supplement|placebo	3
Behavioral|Other	2
Device|Other	2
Device|placebo	2
Diagnostic Test	2
Dietary Supplement|Other	2
Drug|Other|placebo	2
Behavioral|Dietary Supplement|Drug	1
Biological|Drug	1
Biological|placebo	1
Combination Product	1
Device|Dietary Supplement|Drug	1
Device|Procedure	1
Diagnostic Test|Drug	1
Dietary Supplement|Drug	1
Drug|placebo|Procedure	1
Drug|Procedure	1
Drug|Radiation	1
Radiation	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country	Study_Count
United States	115
Denmark	34
Canada	15
NA	14
United Kingdom	13
Germany	12
Netherlands	11
France	7
Switzerland	7
Israel	6
United States|Canada	6
Sweden	4
Austria	3
Italy	3
Brazil	2
Korea, Republic of	2
Mexico	2
Saudi Arabia	2
Slovenia	2
Spain	2
United States|Austria|Canada|Germany	2
Australia	1
Austria|Germany|Netherlands|Spain|Sweden	1
Belgium|Netherlands	1
China	1
Colombia	1
Denmark|Netherlands	1
Egypt	1
Finland	1
Hong Kong	1
Ireland	1
Israel|Slovenia	1
Israel|Slovenia|Sweden	1
Jordan	1
Turkey	1
United States|Australia|New Zealand	1
United States|Austria|Canada	1
United States|Germany|Slovenia	1
United States|Italy	1
United States|United Kingdom	1

Sites per Study

Site_count	Study_Count
1	229
2	23
3	9
4	2
5	7
6	1
7	5
8	2
9	1
17	1
18	1
23	1
39	1

Phase

Phase	Study_Count
N/A	154
Phase 2	33
Phase 1	25
Phase 4	25
Early Phase 1	15
Phase 3	15
Phase 1/Phase 2	13
Phase 2/Phase 3	3

Number of Arms

Number_of_Arms	Count_of_Studies
1	49
2	162
3	37
4	17
5	2
6	5
9	1
NA	10

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	11.00000	3.0000	1.00	5.00000	5.00	10.00000	16.0000	5.00
1st Qu.	17.50000	17.0000	15.00	6.00000	14.75	14.00000	41.0000	13.00
Median	32.00000	29.0000	26.00	18.00000	20.50	18.00000	80.0000	28.00
Mean	57.33333	216.5033	34.28	26.23077	35.75	19.33333	104.2667	162.92
3rd Qu.	60.00000	62.0000	40.00	29.00000	39.00	24.00000	120.5000	100.00
Max.	200.00000	21000.0000	111.00	75.00000	128.00	30.00000	494.0000	2346.00

Trial Group Type

group_type	Group_Count
Experimental	288
Active Comparator	158
Placebo Comparator	74
Other	45
No Intervention	34
NA	10
Sham Comparator	2

Intervention Model

intervention_model	Study_Count
Crossover Assignment	127
Parallel Assignment	90
Single Group Assignment	52
Factorial Assignment	8
Sequential Assignment	5
NA	1

Primary Purpose

primary_purpose	Study_Count
Treatment	140
Basic Science	41
Prevention	40
Diagnostic	22
Other	19
NA	10
Supportive Care	5
Health Services Research	4
Device Feasibility	2

Observational Studies

Studies by Country

Country	Study_Count
United States	28
Denmark	6
NA	6
France	4
Germany	3
United Kingdom	3
Argentina|Austria|Bulgaria|Canada|Croatia|Czechia|Denmark|Finland|Germany|Hungary|India|Israel|Lebanon|Malaysia|Mexico|Netherlands|Poland|Romania|Russian Federation|Saudi Arabia|Serbia|Slovakia|Slovenia|Sweden	1
Brazil	1
Canada	1
Hungary	1
India	1
Italy	1
Korea, Republic of	1
Netherlands	1
Saudi Arabia	1
Slovenia	1
Switzerland	1

Sites per Study

Site_count	Study_Count
1	54
3	2
5	1
6	2
24	1
75	1

Enrollment Metrics

Measure	Observational
Min	2
1st Qu	26
Median	62
Mean	1696324
3rd Qu	330
Max	99999999

Observation Model

observational_model	Study_Count
Cohort	25
Case-Only	10
Case-Control	9
Other	5
NA	4
Case-Crossover	3
Case Control	2
Defined Population	1
Defined Population, Natural History	1
Ecologic or Community	1

Time Perspective

time_perspective	Study_Count
Prospective	38
Cross-Sectional	10
Retrospective	7
Other	2
NA	2
Cross-Sectional, Prospective	1
Longitudinal, Prospective	1

Registries

Studies by Country

Country	Study_Count
United States	1

Sites per Study

Site_count	Study_Count
1	1

Enrollment Metrics

Measure	Registries
Min	100
1st Qu	100
Median	100
Mean	100
3rd Qu	100
Max	100

Registry Model

observational_model	Study_Count
Cohort	1

Time Perspective

time_perspective	Study_Count
Cross-Sectional	1

Follow-up

target_duration	Study_Count
3 Weeks	1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT04081766	Pharmacist-Led Study in Controlling Hypoglycemia in Older Adults With Type 2 Diabetes Mellitus	https://ClinicalTrials.gov/show/NCT04081766	Recruiting	University of Lincoln	2020-11-30
NCT03895697	A Trial to Compare the Efficacy and Safety of 2 Different Batches of Subcutaneous Dasiglucagon in Patients With T1DM	https://ClinicalTrials.gov/show/NCT03895697	Completed	Zealand Pharma	2019-07-29
NCT03410277	Recurrent Hypoglycemia in Type 1 Diabetes (Aim 1)	https://ClinicalTrials.gov/show/NCT03410277	Recruiting	University of Minnesota	2023-12-31
NCT03406897	Pilot Study of OMEGA-3 and Vitamin D in High-Dose in Type I Diabetic Patients	https://ClinicalTrials.gov/show/NCT03406897	Recruiting	University of Miami	2022-09-30
NCT03373435	Safety and Efficacy of Exendin 9-39 in Patients With Postbariatric Hypoglycemia	https://ClinicalTrials.gov/show/NCT03373435	Completed	Eiger BioPharmaceuticals	2018-09-19
NCT03359590	Sitagliptin and the Risk for Hypoglycaemia in Type 2 Diabetes Patients	https://ClinicalTrials.gov/show/NCT03359590	Completed	Profil Institut für Stoffwechselforschung GmbH	2019-07-17
NCT03353415	Continuous Glucose Monitoring to Reduce Hypoglycemia and Improve Safety in Patients With Hypoglycemia After Gastric Surgery	https://ClinicalTrials.gov/show/NCT03353415	Recruiting	Joslin Diabetes Center	2019-10-31
NCT03344185	The Effect of Glycaemic Index Variation on Blood Glucose and Mood in Healthy Participants Across the Day	https://ClinicalTrials.gov/show/NCT03344185	Completed	University of Reading	2016-10-31
NCT03339453	A Study of Nasal Glucagon in Participants With Type 1 Diabetes Mellitus	https://ClinicalTrials.gov/show/NCT03339453	Completed	Eli Lilly and Company	2017-12-17
NCT03286816	The Effect of Intravenous Lactate on Brain Lactate Concentrations During Hypoglycemia	https://ClinicalTrials.gov/show/NCT03286816	Completed	Radboud University	2017-05-31
NCT03255629	Closed-Loop Glucagon Pump for Treatment of Post-Bariatric Hypoglycemia	https://ClinicalTrials.gov/show/NCT03255629	Completed	Joslin Diabetes Center	2018-08-22
NCT03252704	Post-prandial Glycemic Response to Fiber in Healthy Adults	https://ClinicalTrials.gov/show/NCT03252704	Completed	Ingredion Incorporated	2016-10-31
NCT03234491	Improving Post-Prandial Blood Glucose Control With Afrezza During Closed-Loop Therapy	https://ClinicalTrials.gov/show/NCT03234491	Recruiting	Yale University	2021-08-01
NCT03216226	A Trial to Evaluate the Immunogenicity of Dasiglucagon and GlucaGen in Patients With Type 1 Diabetes Mellitus	https://ClinicalTrials.gov/show/NCT03216226	Completed	Zealand Pharma	2018-02-14
NCT03215914	Hybrid Closed Loop Insulin Delivery System in Hypoglycemia	https://ClinicalTrials.gov/show/NCT03215914	Active, not recruiting	University of Pennsylvania	2021-12-31
NCT03200782	Postprandial Hypoglycemia in Patients After Bariatric Surgery With Empagliflozin and Anakinra - The Hypo-BEAR-Study	https://ClinicalTrials.gov/show/NCT03200782	Completed	University Hospital, Basel, Switzerland	2018-09-21
NCT03182842	FreeStyle Libre FGM During Summer Camp for Children With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03182842	Completed	University of Ljubljana, Faculty of Medicine	2017-07-01
NCT03182192	GLP1R-imaging in Hypoglycemia	https://ClinicalTrials.gov/show/NCT03182192	Recruiting	Radboud University	2021-02-01
NCT03165786	A Cognitive Behavioral Intervention to Reduce Fear of Hypoglycemia in Young Adults With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03165786	Completed	University of Illinois at Chicago	2018-01-16
NCT03163511	A Safety, Tolerability, and Efficacy Study of VC-02â„¢ Combination Product in Subjects With Type 1 Diabetes Mellitus and Hypoglycemia Unawareness	https://ClinicalTrials.gov/show/NCT03163511	Recruiting	ViaCyte	2020-09-30
NCT03149770	Naloxone, Hypoglycemia and Exercise	https://ClinicalTrials.gov/show/NCT03149770	Recruiting	University of Minnesota	2020-12-31
NCT03130101	Insulin Management for Exercise in Patients With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03130101	Completed	York University	2018-02-01
NCT03112343	Information and Communication Technology Based Centralized Clinical Trial Monitoring System for Insulin Dose Adjustment	https://ClinicalTrials.gov/show/NCT03112343	Completed	Samsung Medical Center	2018-09-30
NCT03103009	Treatment Plan for an Individual Patient With Pasireotide for Hyperinsulinemic Hypoglycemia	https://ClinicalTrials.gov/show/NCT03103009	Recruiting	University of Colorado, Denver	2022-03-22
NCT03102801	A Study to Identify Biomarkers of Hypoglycaemia in Patients With Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT03102801	Completed	University of Hull	2018-01-10
NCT03090451	Exercise Physiology Study	https://ClinicalTrials.gov/show/NCT03090451	Completed	Oregon Health and Science University	2018-12-14
NCT03078491	Technological Advances in Glucose Management in Older Adults	https://ClinicalTrials.gov/show/NCT03078491	Recruiting	Joslin Diabetes Center	2021-07-31
NCT03076775	Euglycemia After Antenatal Late Preterm Steroids, the E-ALPS Study	https://ClinicalTrials.gov/show/NCT03076775	Recruiting	University of North Carolina, Chapel Hill	2020-05-30
NCT03039933	Intervention to Reduce Fear of Hypoglycemia and Optimize Type 1 Diabetes Outcomes	https://ClinicalTrials.gov/show/NCT03039933	Active, not recruiting	University of Colorado, Denver	2020-07-31
NCT03032523	Detecting Neonatal Hypoglycemia Using Real-Time Continuous Glucose Monitoring (CGM)	https://ClinicalTrials.gov/show/NCT03032523	Completed	Stanford University	2018-04-01
NCT03028220	Impact on Hypoglycaemia Awareness of Real Time CGM and Intermittent Continuous Glucose Data	https://ClinicalTrials.gov/show/NCT03028220	Completed	Imperial College London	2017-02-28
NCT03022058	Evaluation of the EarEEG System for Detection of Hypoglycaemia-induced Changes in the EEG in Subjects With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03022058	Completed	Odense University Hospital	2017-11-16
NCT03014011	Effects of Mild Hypoglycaemia on Cognitive Function in Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT03014011	Completed	Bispebjerg Hospital	2018-07-23
NCT02969343	Patient Safety Learning Laboratory: Making Acute Care More Patient-Centered	https://ClinicalTrials.gov/show/NCT02969343	Completed	Brigham and Women’s Hospital	2018-12-31
NCT02966275	Post Bariatric Closed Loop Glucagon Trial	https://ClinicalTrials.gov/show/NCT02966275	Completed	Massachusetts General Hospital	2017-12-31
NCT02940873	Hypoglycaemia Awareness Restoration Programme	https://ClinicalTrials.gov/show/NCT02940873	Active, not recruiting	King’s College London	2021-05-31
NCT02925676	Evaluation of the Hypoglycaemia Alarm Device Hyposafe H02	https://ClinicalTrials.gov/show/NCT02925676	Recruiting	UNEEG Medical A/S	2020-08-31
NCT02881060	The Late Effects of Ethanol Intake on the Glucose Response to Subcutaneous Glucagon in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT02881060	Completed	Hvidovre University Hospital	2017-01-26
NCT02875925	Outcomes Study of MTM in a Medicare ACO	https://ClinicalTrials.gov/show/NCT02875925	Completed	HealthEast Care System	2017-12-31
NCT02871180	Late Night Snack and Insulin Glargine	https://ClinicalTrials.gov/show/NCT02871180	Completed	Diabeteszentrum Bad Lauterberg im Harz	2016-08-31
NCT02866435	Identifying the Brain Substrates of Hypoglycemia Unawareness in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT02866435	Completed	University of Minnesota	2019-09-30
NCT02829593	Measurement of Glucose Metabolism in Humans: Effect of Recurrent Hypoglycemia on Hypothalamic GABA	https://ClinicalTrials.gov/show/NCT02829593	Recruiting	University of Minnesota	2021-05-31
NCT02823665	The Effects of Bariatric Surgeries on Glucose Metabolism	https://ClinicalTrials.gov/show/NCT02823665	Recruiting	The University of Texas Health Science Center at San Antonio	2022-07-31
NCT02778269	Predicting Hypoglycaemia and Arrhythmias in the Patient With Diabetes and CKD - Validation Study	https://ClinicalTrials.gov/show/NCT02778269	Completed	RWTH Aachen University	2017-03-31
NCT02771574	Efficacy, Tolerability and Pharmacokinetics of Subcutaneous Exendin (9-39) in Patients With Post Bariatric Hypoglycemia	https://ClinicalTrials.gov/show/NCT02771574	Completed	Stanford University	2017-06-30
NCT02747680	Cerebral Responses to Insulin Induced Hypoglycemia	https://ClinicalTrials.gov/show/NCT02747680	Recruiting	University of Minnesota	2020-12-31
NCT02735031	Exenatide and Impaired Hypoglycaemic Awareness in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT02735031	Completed	Radboud University	2018-03-28
NCT02733588	Delivery of G-Pump™ (Glucagon Infusion) From an OmniPod® to Prevent Hypoglycemia in Post-Bariatric Surgery Patients	https://ClinicalTrials.gov/show/NCT02733588	Completed	Xeris Pharmaceuticals	2017-04-05
NCT02714972	Reduction of Nocturnal Hypoglycemia and Hyperglycemia in the Home Using Predictive Algorithms, Pump Suspension, and Insulin Dosing in Children and Young Adolescents	https://ClinicalTrials.gov/show/NCT02714972	Completed	Jaeb Center for Health Research	2017-03-31
NCT02700048	Intra-nasal Naloxone for Treatment of Impaired Awareness of Hypoglycemia	https://ClinicalTrials.gov/show/NCT02700048	Active, not recruiting	University of Minnesota	2021-11-30
NCT02687893	Effect of Hypoglycemia on Sleep	https://ClinicalTrials.gov/show/NCT02687893	Completed	Oregon Health and Science University	2016-09-30
NCT02685852	Evaluating Exenatide for the Treatment of Postprandial Hyperinsulinemic Hypoglycemia	https://ClinicalTrials.gov/show/NCT02685852	Completed	University of Minnesota	2019-07-10
NCT02665715	Can Postprandial Reactive Hypoglycaemia be Reduced in Patients After Roux-en-Y Gastric Bypass With a Low Carbohydrate Diet?	https://ClinicalTrials.gov/show/NCT02665715	Completed	Bispebjerg Hospital	2016-06-30
NCT02660242	The Use of Mini-dose Glucagon to Prevent Exercise-induced Hypoglycemia in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT02660242	Completed	Jaeb Center for Health Research	2017-02-15
NCT02660008	Single Doses of ZP4207 Adm. sc to Hypoglycemic TD1 pt. to Describe the PK and PD of ZP4207 as Comp. to Marketed Glucagon	https://ClinicalTrials.gov/show/NCT02660008	Completed	Zealand Pharma	2016-06-30
NCT02657213	Study of Insulin Pump in Prevention of Low Glucose Events in Adults With Type 1 Diabetes at Risk of Severe Hypoglycemia	https://ClinicalTrials.gov/show/NCT02657213	Completed	University Hospital, Grenoble	2017-06-30
NCT02657083	Prevention of Hypoglycemia After Exercise Using Closed Loop System in Children and Adolescents With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT02657083	Completed	University of Ljubljana, Faculty of Medicine	2016-06-30
NCT02656069	Safety and Efficacy of G-Pen Compared to Lilly Glucagon for Hypoglycemia Rescue in Adult Type 1 Diabetics	https://ClinicalTrials.gov/show/NCT02656069	Completed	Xeris Pharmaceuticals	2017-08-14
NCT02631265	Insulin-based Strategies to Prevent Hypoglycemia During Exercise	https://ClinicalTrials.gov/show/NCT02631265	Completed	Institut de Recherches Cliniques de Montreal	2017-09-30
NCT02590016	Glucose Control During Labour in Gestational Diabetes Mellitus With Insulin Treatment: A Randomized Controlled Trial	https://ClinicalTrials.gov/show/NCT02590016	Recruiting	Tampere University Hospital	2020-12-31
NCT02583776	Continuous Glucose Monitoring and Preterm Infants	https://ClinicalTrials.gov/show/NCT02583776	Completed	University Hospital Padova	2016-04-30
NCT03346746	Utilizing GI: Exploring an Optimum Glycaemic Profile for Cognitive Function Across the Day	https://ClinicalTrials.gov/show/NCT03346746	Completed	University of Reading	2017-08-30
NCT02527993	Treatment of Hypoglycemia Following Gastric Bypass Surgery	https://ClinicalTrials.gov/show/NCT02527993	Completed	Zealand University Hospital	2017-04-08
NCT02523222	Prophylactic Dextrose Gel for Newborns at High-risk for Hypoglycemia	https://ClinicalTrials.gov/show/NCT02523222	Completed	Baylor University	2016-10-31
NCT02471040	Brain Ketone Metabolism in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT02471040	Recruiting	Yale University	2020-12-31
NCT02459938	Safety and Efficacy of ZP-Glucagon to Injectable Glucagon for Hypoglycemia	https://ClinicalTrials.gov/show/NCT02459938	Completed	Zosano Pharma Corporation	2015-08-31
NCT02445781	Differing Levels of Hypoglycemia	https://ClinicalTrials.gov/show/NCT02445781	Recruiting	University of Maryland, Baltimore	2020-12-31
NCT02438189	Reduction of Nocturnal Hypoglycemia and Hyperglycemia in the Home Using Predictive Algorithms	https://ClinicalTrials.gov/show/NCT02438189	Completed	Jaeb Center for Health Research	2016-03-31
NCT02424500	Multi-Center Study Comparing Efficacy and Safety of Frequently Modified Insulin Therapy	https://ClinicalTrials.gov/show/NCT02424500	Completed	Hygieia Research LLC	2017-06-30
NCT02423980	G-Penâ„¢ for Hypoglycemia Rescue in T1D Patients	https://ClinicalTrials.gov/show/NCT02423980	Completed	Xeris Pharmaceuticals	2015-05-31
NCT02403648	Pharmacokinetics and Pharmacodynamics of BIOD-961 vs. Marketed Glucagons	https://ClinicalTrials.gov/show/NCT02403648	Completed	Biodel	2015-03-31
NCT02402933	Clinical Usability of Nasal Glucagon in Treatment of Hypoglycemia in Children and Adolescents	https://ClinicalTrials.gov/show/NCT02402933	Completed	Eli Lilly and Company	2015-08-31
NCT02402153	Evaluation of Hypo-Safe Hypoglycaemia Alarm Device - the Pilot 2 Study - Healthy Subjects	https://ClinicalTrials.gov/show/NCT02402153	Completed	UNEEG Medical A/S	2017-01-31
NCT02390141	Multiple Ascending Doses of ZP4207 Administered to HV to Evaluate the Safety, Tolerability, PKs and PDs of ZP4207	https://ClinicalTrials.gov/show/NCT02390141	Completed	Zealand Pharma	2015-07-31
NCT02380339	A Combined Biofeedback-virtual Reality System for Reduction of Fear of Hypoglycemia	https://ClinicalTrials.gov/show/NCT02380339	Recruiting	Hadassah Medical Organization	2019-12-31
NCT02367053	Single Ascending Doses of ZP4207 Administered in HV and in T1D to Evaluate Safety, Tolerability PKs and PDs of ZP4207 Compared to a Comparator	https://ClinicalTrials.gov/show/NCT02367053	Completed	Zealand Pharma	2015-04-30
NCT02336438	The Effect of Glucomannan Soluble Fiber on Glucose Homeostasis in Patients With Roux En Y (RNY) Gastric Bypass Surgery	https://ClinicalTrials.gov/show/NCT02336438	Completed	Bassett Healthcare	2014-11-30
NCT02315300	Predicting Hypoglycaemia and Arrhythmias in the Vulnerable Patient With Diabetes and Chronic Kidney Disease	https://ClinicalTrials.gov/show/NCT02315300	Completed	RWTH Aachen University	2016-05-31
NCT02308293	The Role of Endogenous Lactate in Brain Preservation and Counterregulatory Defenses Against Hypoglycemia	https://ClinicalTrials.gov/show/NCT02308293	Completed	Radboud University	2016-05-31
NCT02302963	USS Virginia Closed-Loop Versus SAP Therapy for Hypoglycemia Reduction in T1D	https://ClinicalTrials.gov/show/NCT02302963	Completed	University of Virginia	2017-01-31
NCT02299479	Adjusting Insulin Delivery to Activity	https://ClinicalTrials.gov/show/NCT02299479	Completed	Boston Children’s Hospital	2017-06-27
NCT02298803	QT Interval Abnormalities in Sulfonylurea Treated Type 2 Diabetes: Relationship to Treatment Induced Hypoglycaemia	https://ClinicalTrials.gov/show/NCT02298803	Completed	Royal Prince Alfred Hospital, Sydney, Australia	2016-01-31
NCT02282254	Closed-loop Control of Overnight Glucose Levels (Artificial Pancreas) in Type 1 Diabètes Adults With Hypoglycemia Unawareness and Documented Nocturnal Hypoglycemia	https://ClinicalTrials.gov/show/NCT02282254	Completed	Institut de Recherches Cliniques de Montreal	2016-07-31
NCT03385707	Hypoglycemia and the Gut Microbiome	https://ClinicalTrials.gov/show/NCT03385707	Recruiting	Joslin Diabetes Center	2019-11-30
NCT02232698	An Evaluation of Novel Glucose Sensing Technology on Hypoglycaemia in Type 1 Diabetes (IMPACT)	https://ClinicalTrials.gov/show/NCT02232698	Completed	Abbott Diabetes Care	2015-10-31
NCT04452396	CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive Hypoglycaemia	https://ClinicalTrials.gov/show/NCT04452396	Recruiting	Barts & The London NHS Trust	2020-11-18
NCT02213003	Allogeneic Islet Cells Transplanted Onto the Omentum	https://ClinicalTrials.gov/show/NCT02213003	Recruiting	University of Miami	2022-05-31
NCT02206152	A Randomized Double Blinded Study to Examine the Use of N-acetyl Cysteine for the Prevention and Treatment of HAAF in Patients With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT02206152	Completed	University of Minnesota	2017-12-31
NCT02205996	The Effects of Hypoglycaemia in People With Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT02205996	Completed	University of Hull	2013-05-31
NCT02192450	Insulin Degludec and Symptomatic Nocturnal Hypoglycaemia	https://ClinicalTrials.gov/show/NCT02192450	Completed	Nordsjaellands Hospital	2019-02-28
NCT02181127	Closed-Loop Glucagon Administration For Hypoglycemia Treatment	https://ClinicalTrials.gov/show/NCT02181127	Completed	Massachusetts General Hospital	2015-06-30
NCT02179281	Prevention of Hypoglycaemia With Predictive Insulin Suspend Using Sensor Augmented Insulin Pump in Children	https://ClinicalTrials.gov/show/NCT02179281	Completed	University of Ljubljana, Faculty of Medicine	2015-02-28
NCT02176096	Comparison of the Effect of a Novel Starch (Glycosade) Versus Gastrostomy Tube-Dextrose Infusion on Overnight Euglycaemia Control in Children With Glycogen Storage Disease Type I: Open Label Demonstration Trial	https://ClinicalTrials.gov/show/NCT02176096	Completed	University of Manitoba	2016-08-31
NCT02171130	Clinical Usability of Intranasal Glucagon in Treatment of Hypoglycemia	https://ClinicalTrials.gov/show/NCT02171130	Completed	Eli Lilly and Company	2015-08-31
NCT02146404	The Effect of Hypoglycaemia on Brain Lactate Accumulation and Cerebral Blood Flow	https://ClinicalTrials.gov/show/NCT02146404	Completed	Radboud University	2015-10-31
NCT02135068	Preventing Hypoglycemia During Exercise With Proactive Snacking on Closed Loop	https://ClinicalTrials.gov/show/NCT02135068	Completed	Yale University	2016-06-30
NCT02127541	New Imaging Procedure for the Localisation of Insulinoma	https://ClinicalTrials.gov/show/NCT02127541	Completed	University Hospital, Basel, Switzerland	2017-11-30
NCT02107326	Randomized Crossover Study to Test the Impact of Using a Software for Smartphones and Tablets in Treating Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT02107326	Completed	University Hospital, Geneva	2017-08-15
NCT02086227	Bioequivalence of Fresenius Kabi USA, LLC Glucagon for SC Injection Compared to Glucagon for Injection (Bedford Laboratories)	https://ClinicalTrials.gov/show/NCT02086227	Completed	Fresenius Kabi USA, LLC	2013-06-30
NCT02081014	Safety and Efficacy Study of Mini-Dose Glucagon (G-Pen Mini) in Patients With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT02081014	Completed	Xeris Pharmaceuticals	2014-11-30
NCT02081001	PK/PD Study With G-Pump (Glucagon Infusion) in T1DM Patients	https://ClinicalTrials.gov/show/NCT02081001	Completed	Xeris Pharmaceuticals	2014-08-31
NCT02068638	Impact of Physical Activity on Blood Glucose Stability and Energy Stores in Individuals With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT02068638	Completed	University Hospital Inselspital, Berne	2016-07-31
NCT02057848	Carbohydrates to Prevent Hypoglycaemia During Physical Activity in Patients With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT02057848	Completed	Diabeteszentrum Bad Lauterberg im Harz	2014-02-28
NCT01283126	Blood/Interstitial Glucose Measurements and Cognitive Function During Hypoglycemia and Recovery	https://ClinicalTrials.gov/show/NCT01283126	Completed	Joslin Diabetes Center	2014-10-31
NCT01272583	Dipeptidyl Peptidase-4 Inhibitors and Alpha-cell Recovery	https://ClinicalTrials.gov/show/NCT01272583	Completed	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	2012-06-30
NCT02056353	Multicentre LOGIC-Insulin Algorithm-guided Versus Nurse-directed Blood Glucose Control During Critical Illness (LOGIC-2)	https://ClinicalTrials.gov/show/NCT02056353	Completed	KU Leuven	2015-04-30
NCT02047643	Accelerometer Use in the Prevention of Exercise-Associated Hypoglycemia in Type 1 Diabetes: Outpatient Exercise Protocol	https://ClinicalTrials.gov/show/NCT02047643	Completed	Stanford University	2014-05-01
NCT02020629	Study on Lixisenatide and Counterregulation to Hypoglycemia	https://ClinicalTrials.gov/show/NCT02020629	Completed	Lund University	2014-08-31
NCT03356457	Development of Agents to Diminish the Risk of Hypoglycemia-induced Brain Injury in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03356457	Recruiting	Yale University	2020-11-30
NCT02007278	Glycemic Excursions in Type 2 Diabetic Patients With Vildagliptin and Metformin Versus Vildagliptin and Glimepiride	https://ClinicalTrials.gov/show/NCT02007278	Completed	Novartis	2016-02-22
NCT01994746	Efficacy and Safety of Nasal Glucagon for Treatment of Hypoglycemia in Adults	https://ClinicalTrials.gov/show/NCT01994746	Completed	Eli Lilly and Company	2015-01-31
NCT01980914	Hypoglycemia (Low Blood Sugar) and the Heart	https://ClinicalTrials.gov/show/NCT01980914	Completed	University of British Columbia	2019-09-30
NCT01972152	Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of G-Pen(TM) (Glucagon Injection) to Treat Severe Hypoglycemia	https://ClinicalTrials.gov/show/NCT01972152	Completed	Xeris Pharmaceuticals	2014-02-28
NCT01942239	Real-time Continuous Glucose Monitoring in Very Low Birth Weight Neonates	https://ClinicalTrials.gov/show/NCT01942239	Completed	University Hospital, Tours	2009-11-30
NCT01933490	Post-Gastric Bypass Hypoglycemia	https://ClinicalTrials.gov/show/NCT01933490	Completed	University of Minnesota	2014-08-31
NCT01923688	Preventing Hypoglycemia	https://ClinicalTrials.gov/show/NCT01923688	Completed	Washington University School of Medicine	2011-12-31
NCT01922817	DPP4inhibitors in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT01922817	Completed	University of Dundee	2014-04-30
NCT01919788	Intracellular Counter-regulatory Mechanisms Following Low Blood Glucose	https://ClinicalTrials.gov/show/NCT01919788	Completed	University of Aarhus	2014-04-30
NCT01919385	Feasibility Study Assessing the Ability of an Insulin Pump-controlling Algorithm to Minimize Hypoglycemia	https://ClinicalTrials.gov/show/NCT01919385	Completed	Animas Corporation	2013-09-30
NCT01865760	Etiology, Assessment and Treatment of Post-gastric Bypass Severe Hypoglycemia	https://ClinicalTrials.gov/show/NCT01865760	Completed	University of Aarhus	2016-03-31
NCT01858896	GLP-1 and Hypoglycemia	https://ClinicalTrials.gov/show/NCT01858896	Active, not recruiting	University of Maryland, Baltimore	2020-12-31
NCT01823341	Outpatient Reduction of Nocturnal Hypoglycemia by Using Predictive Algorithms and Pump Suspension in Children	https://ClinicalTrials.gov/show/NCT01823341	Completed	Jaeb Center for Health Research	2014-09-30
NCT01816893	Hypoglycemia and Autonomic Nervous System Function	https://ClinicalTrials.gov/show/NCT01816893	Completed	Brigham and Women’s Hospital	2007-11-06
NCT02025296	Ubiquitous Healthcare Service With Multifactorial Intervention in Diabetes Care	https://ClinicalTrials.gov/show/NCT02025296	Completed	Seoul National University Bundang Hospital	2014-08-31
NCT01789593	A Trial Investigating the Effect of Acute Hypoglycaemia on Cognitive Function and Brain Activation Patterns in Subjects With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT01789593	Completed	Novo Nordisk A/S	2013-12-01
NCT01787903	The Effects of RT-CGM on Glycemia and QoL in Patients With T1DM and IHA	https://ClinicalTrials.gov/show/NCT01787903	Completed	VU University Medical Center	2016-04-30
NCT01780272	A Trial to Investigate the Impact of Nocturnal Hypoglycaemia on Sleep in Subjects With Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT01780272	Completed	Novo Nordisk A/S	2013-09-30
NCT01739283	GIP and GLP-1 in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT01739283	Completed	University Hospital, Gentofte, Copenhagen	2013-04-30
NCT01714895	Effect of Different Plasma Insulin Levels on the Accuracy of Continuous Subcutaneous Glucose Monitoring	https://ClinicalTrials.gov/show/NCT01714895	Completed	Fundación para la Investigación del Hospital Clínico de Valencia	2012-09-30
NCT01672255	Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus (DM)	https://ClinicalTrials.gov/show/NCT01672255	Recruiting	University of Maryland, Baltimore	2020-12-31
NCT01614769	Effects of Glimepiride on Recovery From Hypoglycemia in Participants With Type 2 Diabetes Mellitus (MK-0000-253)	https://ClinicalTrials.gov/show/NCT01614769	Completed	Merck Sharp & Dohme Corp.	2013-01-09
NCT01581801	Bariatric Surgery and Reactive Hypoglycemia	https://ClinicalTrials.gov/show/NCT01581801	Completed	Catholic University of the Sacred Heart	2015-03-31
NCT01563887	Identifying Driving Risk Factors in Type 1 Diabetes and Their Reduction Via Internet Program (DiabetesDriving.Com)	https://ClinicalTrials.gov/show/NCT01563887	Completed	University of Virginia	2014-10-31
NCT01556594	Safety and Efficacy of a Novel Glucagon Formulation in Type 1 Diabetic Patients Following Insulin-induced Hypoglycemia	https://ClinicalTrials.gov/show/NCT01556594	Completed	Eli Lilly and Company	2012-07-31
NCT01536665	The Effect of Liraglutide Adjunct to Insulin on Glucagon Response to Hypoglycaemia in Subjects With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT01536665	Completed	Novo Nordisk A/S	2012-08-31
NCT01526044	Continuous Glucose Monitoring by Subcutaneous Measurement Compared to Frequent Point of Care Measurement by Accu Chek in Critically Ill Patients	https://ClinicalTrials.gov/show/NCT01526044	Completed	Onze Lieve Vrouwe Gasthuis	2012-04-30
NCT01509157	MDRS for Prevention of Nocturnal Hypoglycemia	https://ClinicalTrials.gov/show/NCT01509157	Completed	Rabin Medical Center	2013-02-28
NCT01488136	Use of Diazoxide in Acute Hypoglycaemia	https://ClinicalTrials.gov/show/NCT01488136	Completed	University of Dundee	2013-03-31
NCT01487798	Frequency of Episodes of Hypoglycaemia During Treatment With Biphasic Insulin Aspart 30 in Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT01487798	Completed	Novo Nordisk A/S	2003-11-30
NCT01474889	Glucose Counterregulation in Long Standing Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT01474889	Active, not recruiting	University of Pennsylvania	2020-12-31
NCT01468454	Phase II Safety and Efficacy Study of F-DOPA PET/CT in Children With Hyperinsulinemic Hypoglycemia	https://ClinicalTrials.gov/show/NCT01468454	Completed	Children’s Hospital of Philadelphia	2014-06-30
NCT01414556	GIP Effects at Insulin Induced Hypoglycemia in Patients With Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT01414556	Completed	University Hospital, Gentofte, Copenhagen	2012-07-31
NCT01409382	Maternal Lifestyle and Neonatal Hypoglycemia	https://ClinicalTrials.gov/show/NCT01409382	Completed	Hospital dos Servidores do Estado do Rio de Janeiro	2013-04-30
NCT01401751	Feasibility Study Assessing The Ability Of An Insulin Pump-Controlling Algorithm To Minimize Hypoglycemia And Hyperglycemia In Patients With Type 1 Diabetes In A Clinical Research Setting	https://ClinicalTrials.gov/show/NCT01401751	Completed	Animas Corporation	2011-11-01
NCT01394627	Hypoglycemia and the Mineralocorticoid Receptor	https://ClinicalTrials.gov/show/NCT01394627	Completed	Brigham and Women’s Hospital	2016-08-31
NCT01390259	Hypoglycemia Prevention After Exercise in Adolescent T1DM Patients Using a Control to Range System	https://ClinicalTrials.gov/show/NCT01390259	Completed	University of Virginia	2011-02-28
NCT01383889	Acute Maternal and Fetal Effects of Exercise in Pregnancy	https://ClinicalTrials.gov/show/NCT01383889	Completed	Instituto Materno Infantil Prof. Fernando Figueira	2012-12-31
NCT01347801	Mechanisms of Insulin Resistance in Critical Illness: Role of Systemic Inflammation and GLP-1	https://ClinicalTrials.gov/show/NCT01347801	Completed	Rigshospitalet, Denmark	2014-09-30
NCT01337362	Recurrent Hypoglycaemia in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT01337362	Completed	Hillerod Hospital, Denmark	2013-06-30
NCT04449692	Low-dose Dasiglucagon for Prevention of Insulin-Induced Hypoglycemia in People With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT04449692	Recruiting	Steno Diabetes Center Copenhagen	2021-02-01
NCT04422145	Hypoglycemia Requiring Emergency Services Intervention: Patient Characteristics, Outcome and Cardiovascular Risk Profile	https://ClinicalTrials.gov/show/NCT04422145	Completed	University of Leeds	2017-12-18
NCT04392843	Effect of Fasting on Insulin-induced Hypoglycemia Counterregulation in Healthy Humans	https://ClinicalTrials.gov/show/NCT04392843	Recruiting	University of Cincinnati	2022-05-31
NCT04328896	Telemedicine Monitoring of Nocturnal Incidents	https://ClinicalTrials.gov/show/NCT04328896	Completed	University of Southern California	2018-11-30
NCT04266379	Efficacy of Closed-loop Insulin Therapy in Adults Prone to Hypoglycemia	https://ClinicalTrials.gov/show/NCT04266379	Recruiting	University Hospital, Montpellier	2020-10-01
NCT04233138	SUPPORT Online Training Platform for Type 1 Diabetes Self-management Education and Support (SUPPORT)	https://ClinicalTrials.gov/show/NCT04233138	Enrolling by invitation	McGill University	2021-01-01
NCT04207619	Evaluating Glial Acetate Metabolism as a Biomarker of Hypoglycemic Counterregulation	https://ClinicalTrials.gov/show/NCT04207619	Recruiting	Pennington Biomedical Research Center	2021-02-28
NCT04185766	Prevention of Hypoglycaemia by Oral 40% Destrogel	https://ClinicalTrials.gov/show/NCT04185766	Completed	Fondazione Poliambulanza Istituto Ospedaliero	2019-05-05
NCT04177147	Primary Care Clinicians’ Responses to a Hypoglycemia Risk Calculator for Diabetes Mellitus in Ambulatory Care	https://ClinicalTrials.gov/show/NCT04177147	Completed	Indiana University	2016-09-30
NCT04159948	Preoperative Carbohydrate Drink Prior to Elective Caesarean Section	https://ClinicalTrials.gov/show/NCT04159948	Recruiting	Coombe Women and Infants University Hospital	2020-03-30
NCT04098549	The Effect of Rapid and Slow Glucose Fall on the Subsequent Glucose Production in People With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT04098549	Completed	Steno Diabetes Center Copenhagen	2020-01-15
NCT04089462	Effects of Frequency and Duration of Exercise in People With Type 1 Diabetes A Randomized Crossover Study	https://ClinicalTrials.gov/show/NCT04089462	Active, not recruiting	Steno Diabetes Center Copenhagen	2020-10-15
NCT04064203	The Effect of Insulin-induced Hypoglycaemia on Gut-derived Glucagon Secretion (Px-Hypo)	https://ClinicalTrials.gov/show/NCT04064203	Completed	University Hospital, Gentofte, Copenhagen	2018-09-20
NCT04053712	Dual-hormone Closed-loop Glucose Control in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT04053712	Recruiting	Steno Diabetes Center Copenhagen	2020-07-22
NCT04050553	A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus	https://ClinicalTrials.gov/show/NCT04050553	Recruiting	Eli Lilly and Company	2021-05-25
NCT03241706	Liver Glycogen and Hypoglycemia in Humans	https://ClinicalTrials.gov/show/NCT03241706	Recruiting	University of Cincinnati	2022-05-31
NCT04035993	The HEADWIND-Study	https://ClinicalTrials.gov/show/NCT04035993	Recruiting	University Hospital Inselspital, Berne	2020-07-31
NCT04025762	24/7 Closed-loop in Older Subjects With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT04025762	Recruiting	University of Cambridge	2021-06-30
NCT04016155	Flash Glucose Monitoring in Reduction of Hypoglycaemia in Diabetic Patients With Chronic Kidney Disease	https://ClinicalTrials.gov/show/NCT04016155	Recruiting	Chinese University of Hong Kong	2021-11-30
NCT03984370	Dasiglucagon in the Treatment of Postprandial Hypoglycaemia After Roux-en-Y Gastric Bypass	https://ClinicalTrials.gov/show/NCT03984370	Completed	University Hospital, Gentofte, Copenhagen	2020-02-26
NCT03976271	Consequences of Hypoglycaemia on Cardiovascular and Inflammatory Responses	https://ClinicalTrials.gov/show/NCT03976271	Recruiting	Radboud University	2020-10-04
NCT03970772	Mini-Dose Glucagon to Treat Fasting-induced Hypoglycemia During Ramadan	https://ClinicalTrials.gov/show/NCT03970772	Recruiting	Qassim University	2019-06-15
NCT03970720	Restoration of Hypoglycemia Awareness With Metoclopramide	https://ClinicalTrials.gov/show/NCT03970720	Recruiting	University of Utah	2024-03-31
NCT03930368	Application of Raw Corn Starch on Patients With Insulinoma	https://ClinicalTrials.gov/show/NCT03930368	Recruiting	Peking Union Medical College Hospital	2019-12-31
NCT03882463	Interest of SmartGuard Technology (Predictive System for Stopping Insulin Before Hypoglycemia) in Children With Type 1 Diabetes Treated With Insulin Pump	https://ClinicalTrials.gov/show/NCT03882463	Recruiting	CHU de Reims	2020-06-30
NCT03879642	Reducing Hypoglycemia Fear in Parents of Young Children With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03879642	Completed	University of Kansas Medical Center	2018-10-01
NCT03868657	The Physiological Effects of Human Ether-a-go-go-Related Gene (hERG)Blockade on Metabolism	https://ClinicalTrials.gov/show/NCT03868657	Enrolling by invitation	University of Copenhagen	2019-09-30
NCT03867344	The Functional Neuroanatomy of the Human Physiological Stress Response	https://ClinicalTrials.gov/show/NCT03867344	Recruiting	Brigham and Women’s Hospital	2024-06-30
NCT03859401	Exercise-Induced Hypoglycemia Prevention in Adults With Type 1 Diabetes Using an Artificial Pancreas	https://ClinicalTrials.gov/show/NCT03859401	Completed	University of Virginia	2020-01-13
NCT03845114	Insulin-based Strategies to Prevent Hypoglycemia During Two Types of Exercise	https://ClinicalTrials.gov/show/NCT03845114	Recruiting	Institut de Recherches Cliniques de Montreal	2021-04-15
NCT03841526	Glucagon Ready-to-Use for the Prevention of Exercise-Induced Hypoglycemia During Aerobic Exercise in Adults With T1D	https://ClinicalTrials.gov/show/NCT03841526	Completed	Xeris Pharmaceuticals	2020-03-23
NCT03802942	Prevention of Hypoglycemia Among Diabetes Patients Admitted to Internal Medicine Departments With Nutritional Care	https://ClinicalTrials.gov/show/NCT03802942	Recruiting	Yoseftal Hospital	2021-12-31
NCT03738865	G-Pen Compared to Glucagen Hypokit for Severe Hypoglycemia Rescue in Adults With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03738865	Completed	Xeris Pharmaceuticals	2019-03-29
NCT03738852	Mechanisms for Restoration of Hypoglycemia Awareness	https://ClinicalTrials.gov/show/NCT03738852	Recruiting	Yale University	2023-12-31
NCT03735225	Evaluation of the Safety, Tolerability and Bioavailability of Dasiglucagon Following Subcutaneous (SC) Compared to IV Administration	https://ClinicalTrials.gov/show/NCT03735225	Completed	Zealand Pharma	2019-06-24
NCT03734718	The Role of Glucose-Dependent Insulinotropic Polypeptide in the Pathological Glucose Homeostasis Of Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03734718	Completed	Steno Diabetes Center Copenhagen	2019-12-12
NCT03730909	The Effect Lactate Administration on Cerebral Blood Flow During Hypoglycemia	https://ClinicalTrials.gov/show/NCT03730909	Recruiting	Radboud University	2019-04-11
NCT03726697	Effect of Tahneek on Hypoglycemia in Newborn Infants	https://ClinicalTrials.gov/show/NCT03726697	Completed	King Abdullah International Medical Research Center	2019-05-22
NCT03713060	Pregnancy Following Gastric Bypass - Consequences for Mother and Child	https://ClinicalTrials.gov/show/NCT03713060	Recruiting	University of Southern Denmark	2021-03-30
NCT03711656	Prediction and Prevention of Nocturnal Hypoglycemia in Persons With Type 1 Diabetes Using Machine Learning Techniques	https://ClinicalTrials.gov/show/NCT03711656	Completed	Hospital Clinic of Barcelona	2019-03-01
NCT03708939	Microbiome and Non-caloric Sweeteners in Humans	https://ClinicalTrials.gov/show/NCT03708939	Enrolling by invitation	Weizmann Institute of Science	2020-08-01
NCT03704818	Dapagliflozin Effects on Hypoglycemia	https://ClinicalTrials.gov/show/NCT03704818	Recruiting	University of California, San Diego	2020-06-30
NCT03688711	Trial to Confirm the Clinical Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Subjects With T1DM	https://ClinicalTrials.gov/show/NCT03688711	Completed	Zealand Pharma	2019-03-11
NCT03674281	The VRIF Trial: Hypoglycemia Reduction With Automated-Insulin Delivery System	https://ClinicalTrials.gov/show/NCT03674281	Completed	University of Virginia	2019-11-21
NCT03667053	Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in T1DM Children	https://ClinicalTrials.gov/show/NCT03667053	Completed	Zealand Pharma	2019-06-28
NCT03665870	Prevention Through Intervention: Telehealth Solution to Deter 911 Calls Due to Hypoglycemia	https://ClinicalTrials.gov/show/NCT03665870	Recruiting	University of Alabama at Birmingham	2020-05-24
NCT03653533	Evaluation of the Function “Stop Before Hypoglycemia” on External Insulin Pump	https://ClinicalTrials.gov/show/NCT03653533	Recruiting	ARAIR Assistance	2019-12-31
NCT04456712	Effect of Ciprofloxacin Versus Levofloxacin on QTc-interval and Dysglycemia	https://ClinicalTrials.gov/show/NCT04456712	Completed	Beni-Suef University	2018-11-30
NCT03609632	Understanding Hypoglycaemia After Bariatric Surgery	https://ClinicalTrials.gov/show/NCT03609632	Completed	University Hospital Inselspital, Berne	2018-11-02
NCT03583268	Determining the Appropriate Intensity of Exercise to Prevent Post-exercise Hypoglycemia in Persons Living With T1D	https://ClinicalTrials.gov/show/NCT03583268	Completed	University of Manitoba	2016-03-31
NCT03570138	Efficacy of Flash Glucose-Sensing Technology on the Occurrence of Cardiac Arrhythmias Associated With Hypoglycemia	https://ClinicalTrials.gov/show/NCT03570138	Recruiting	Poitiers University Hospital	2020-05-01
NCT03556098	Glucose-dependent Insulinotropic Polypeptide as a Safeguard Against Hypoglycemia in Patients With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03556098	Active, not recruiting	Steno Diabetes Center Copenhagen	2020-02-11
NCT03556033	Effect of Dapagliflozin on IAH in T1DM	https://ClinicalTrials.gov/show/NCT03556033	Completed	Radboud University	2019-12-20
NCT03549104	A Cognitive Behavioral Therapy (CBT) Intervention to Reduce Fear of Hypoglycemia in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03549104	Active, not recruiting	University of Illinois at Chicago	2021-06-30
NCT03538015	Carvedilol in Treating Hypoglycemia Unawareness	https://ClinicalTrials.gov/show/NCT03538015	Recruiting	University of Utah	2020-12-31
NCT03514576	Pasireotide in the Treatment of Hypoglycemia Following Gastric Bypass Surgery	https://ClinicalTrials.gov/show/NCT03514576	Enrolling by invitation	Zealand University Hospital	2018-08-01
NCT03508934	Continuous Glucose Monitoring Devices in Hospitalized Veterans With Diabetes	https://ClinicalTrials.gov/show/NCT03508934	Recruiting	VA Office of Research and Development	2022-06-30
NCT03490942	Glucagon Infusion in T1D Patients With Recurrent Severe Hypoglycemia: Effects on Counter-Regulatory Responses	https://ClinicalTrials.gov/show/NCT03490942	Completed	Xeris Pharmaceuticals	2019-11-04
NCT03489967	Treatment of Hypoglycemia in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03489967	Recruiting	Institut de Recherches Cliniques de Montreal	2020-05-31
NCT03460899	Impact of Hypoglycaemia in Patients With Diabetes Mellitus Type 2 on Platelet Activation	https://ClinicalTrials.gov/show/NCT03460899	Completed	Medical University of Graz	2018-06-11
NCT03455985	Effectiveness of a Diabetes Focused Discharge Order Set Among Poorly Controlled Hospitalized Patients Transitioning to Glargine U300 Insulin	https://ClinicalTrials.gov/show/NCT03455985	Recruiting	Ohio State University	2020-04-30
NCT03439072	G-Penâ„¢ Compared to Lilly Glucagon for Hypoglycemia Rescue in Adults With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03439072	Completed	Xeris Pharmaceuticals	2018-04-18
NCT03429946	Hypoglycemia and Autonomic Nervous System Function-B	https://ClinicalTrials.gov/show/NCT03429946	Active, not recruiting	Brigham and Women’s Hospital	2021-01-04
NCT03422471	Hypoglycemia and Autonomic Nervous System Function- B2	https://ClinicalTrials.gov/show/NCT03422471	Recruiting	Brigham and Women’s Hospital	2019-12-28
NCT01219400	Vildagliptin and the Glucagon Response to Hypoglycemia in Insulin-Treated Patients With Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT01219400	Completed	Lund University	2013-10-31
NCT01194479	Effect of Formoterol on the Counterregulatory Hormonal Response to Hypoglycemia in Type 1 Diabetes.	https://ClinicalTrials.gov/show/NCT01194479	Completed	Yale University	2014-08-31
NCT01162499	Role of Glucagon-Like Peptide-1 in Postprandial Hypoglycemia	https://ClinicalTrials.gov/show/NCT01162499	Completed	Children’s Hospital of Philadelphia	2014-12-31
NCT01147276	Vildagliptin and the Glucagon Response to Hypoglycemia in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT01147276	Completed	Lund University	2011-09-30
NCT01116180	Cognitive Function and Electrocardiogram (ECG) During Hypoglycemia and Blockade of the Renin-angiotensin System	https://ClinicalTrials.gov/show/NCT01116180	Completed	Hillerod Hospital, Denmark	2012-08-31
NCT01053078	Naltrexone and Hypoglycemia in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT01053078	Completed	University of Minnesota	2014-06-30
NCT01013402	Investigating the Accuracy of the Home Glucose Monitors in Hypoglycemia	https://ClinicalTrials.gov/show/NCT01013402	Completed	Gulhane School of Medicine	2009-04-30
NCT01005342	Influence of Dietary Fiber-rich Meals on Gene Expression and Postprandial Glucose and Lipid Response	https://ClinicalTrials.gov/show/NCT01005342	Completed	Lund University	2007-06-30
NCT00993720	Effect of GLP-1 on Insulin-dose, Risk of Hypoglycemia and Gastric Emptying Rate in Patients With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT00993720	Completed	Hvidovre University Hospital	2010-10-31
NCT00992901	Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery	https://ClinicalTrials.gov/show/NCT00992901	Recruiting	The University of Texas Health Science Center at San Antonio	2020-07-31
NCT00974051	Use of Terbutaline or a Reduction in Basal Insulin in the Prevention of Nocturnal Hypoglycemia	https://ClinicalTrials.gov/show/NCT00974051	Completed	University of Colorado, Denver	2008-12-31
NCT00882492	GLP 1 for Intraoperative Glycemic Control	https://ClinicalTrials.gov/show/NCT00882492	Completed	University of Pennsylvania	2011-05-31
NCT00882050	Intravenous Exenatide (Byetta) During Surgery	https://ClinicalTrials.gov/show/NCT00882050	Completed	University of Pennsylvania	2016-04-30
NCT00847080	Treatment With Sitagliptin for Reactive Hypoglycemia Secondary to Dysinsulinism	https://ClinicalTrials.gov/show/NCT00847080	Completed	Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran	2010-12-31
NCT00843609	International Navigator Hypoglycaemia Study	https://ClinicalTrials.gov/show/NCT00843609	Completed	University Medical Centre Ljubljana	2009-12-31
NCT03770637	Glucagon Ready to Use (RTU) in Subjects With Hyperinsulinemic Hypoglycemia After Bariatric Surgery	https://ClinicalTrials.gov/show/NCT03770637	Completed	Xeris Pharmaceuticals	2020-02-26
NCT00831389	Effect of Closed Loop Glucose Control on Exercise-Associated Hypoglycemia	https://ClinicalTrials.gov/show/NCT00831389	Completed	Medtronic Diabetes	2010-11-30
NCT03079921	Adrenergic System in Islet Transplantation	https://ClinicalTrials.gov/show/NCT03079921	Active, not recruiting	University of Pennsylvania	2020-12-31
NCT00817271	To Evaluate the Response to Glucagon During Hypoglycemia	https://ClinicalTrials.gov/show/NCT00817271	Completed	AstraZeneca	2009-04-30
NCT04028960	IN Insulin in Type 1 Diabetes (T1D) Hypoglycemia Unawareness: Safety Only Phase	https://ClinicalTrials.gov/show/NCT04028960	Recruiting	HealthPartners Institute	2020-12-31
NCT00804297	Octreotide for the Treatment of Sulfonylurea-Associated Hypoglycemia	https://ClinicalTrials.gov/show/NCT00804297	Completed	Albert Einstein Healthcare Network	NA
NCT00802971	Idiopathic Reactive Hypoglycaemia and Treatment With Fructo-Oligosaccharide	https://ClinicalTrials.gov/show/NCT00802971	Completed	Asker & Baerum Hospital	2009-04-30
NCT03914547	Home Video-based Telemedicine to Reduce Hypoglycemia Fear in Parents of Young Children	https://ClinicalTrials.gov/show/NCT03914547	Recruiting	University of Kansas Medical Center	2024-03-31
NCT03378635	A Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Type 1 Diabetes Subjects	https://ClinicalTrials.gov/show/NCT03378635	Completed	Zealand Pharma	2018-04-27
NCT02937558	CSI-Glucagon for Prevention of Hypoglycemia in Children With Congenital Hyperinsulinism	https://ClinicalTrials.gov/show/NCT02937558	Completed	Xeris Pharmaceuticals	2018-09-30
NCT02578498	Glucagon Efficiency After High and Low Carbohydrate Diet	https://ClinicalTrials.gov/show/NCT02578498	Completed	Hvidovre University Hospital	2016-03-31
NCT02411578	Mini-Dose Glucagon to Treat Non-Severe Hypoglycemia	https://ClinicalTrials.gov/show/NCT02411578	Completed	Jaeb Center for Health Research	2016-04-30
NCT02225379	Development and Assessment of Feasibility of Non-invasive Multiple Sensor Hypo-Sense as a Tool for Detection of Hypoglycemia	https://ClinicalTrials.gov/show/NCT02225379	Completed	Rabin Medical Center	2016-07-31
NCT01462227	Effect of Naltrexone on Counterregulatory Mechanisms in Hypoglycemia	https://ClinicalTrials.gov/show/NCT01462227	Completed	Yale University	2013-10-31
NCT04142944	The Impact of a Predictive Hypoglycaemia Alert Function in Physical Activity for People With T1DM	https://ClinicalTrials.gov/show/NCT04142944	Active, not recruiting	Imperial College London	2020-08-31
NCT03748433	Assessment of the Impact of Real-Time Continuous Glucose Monitoring on People Presenting With Severe Hypoglycaemia	https://ClinicalTrials.gov/show/NCT03748433	Active, not recruiting	Imperial College London	2020-09-09
NCT03600116	Collection of Breath and Sweat to Identify Indicators of Hypoglycemia	https://ClinicalTrials.gov/show/NCT03600116	Active, not recruiting	Massachusetts General Hospital	2018-11-20
NCT00780650	Mechanisms of Hypoglycemia Associated Autonomic Dysfunction, Q4-Atomoxetine	https://ClinicalTrials.gov/show/NCT00780650	Completed	University of Maryland, Baltimore	2018-08-21
NCT00745186	Pharmacokinetics (PK) and Pharmacodynamics (PD) of Mayne Glucagon for Injection Compared With Glucagen® (Novo Nordisk) in Healthy Volunteers	https://ClinicalTrials.gov/show/NCT00745186	Completed	Hospira, now a wholly owned subsidiary of Pfizer	2007-10-31
NCT00742521	Mechanisms of Hypoglycemia Associated Autonomic Dysfunction, Q.3	https://ClinicalTrials.gov/show/NCT00742521	Completed	Vanderbilt University	2008-11-30
NCT00706693	Skittles(TM) Effective for Treating Hypoglycemia in Children With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT00706693	Completed	University of Calgary	2006-09-30
NCT00678145	Mechanisms Responsible for Hypoglycemia Associated Autonomic Failure	https://ClinicalTrials.gov/show/NCT00678145	Active, not recruiting	Albert Einstein College of Medicine	2022-08-31
NCT00674440	Utility of [F-18] fluoroDOPA for Neonatal Hyperinsulinism	https://ClinicalTrials.gov/show/NCT00674440	Completed	Children’s Hospital of Philadelphia	2008-12-31
NCT00641407	Bedtime Insulins and Oral Antihyperglycemic Drugs in Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT00641407	Completed	University of Campania “Luigi Vanvitelli”	2007-12-31
NCT00615368	Treatment With Erythropoietin and Cognition During Hypoglycaemia	https://ClinicalTrials.gov/show/NCT00615368	Completed	Hillerod Hospital, Denmark	2009-12-31
NCT00609895	The Incidence of Hypoglycemia in Insulin Glargine-Treated Subjects With Diabetes Mellitus Upon Switching Between Bedtime and Morning Dosing	https://ClinicalTrials.gov/show/NCT00609895	Completed	Sanofi	NA
NCT00608348	Sympathetic Nerve Activity During Hypoglycemia and Exercise	https://ClinicalTrials.gov/show/NCT00608348	Completed	Vanderbilt University	2008-07-31
NCT00608179	Glimepiride Induced Insulin Secretion Will be Inhibited by Hypoglycemia	https://ClinicalTrials.gov/show/NCT00608179	Completed	Vanderbilt University	2004-09-30
NCT00607646	Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus	https://ClinicalTrials.gov/show/NCT00607646	Completed	University of Maryland, Baltimore	2018-10-09
NCT00592670	Hypoglycemia Associated Autonomic Failure in Type 1 DM	https://ClinicalTrials.gov/show/NCT00592670	Completed	Vanderbilt University	2007-06-30
NCT00592332	Hypoglycemia Associated Autonomic Failure in Type 1 DM, Q2	https://ClinicalTrials.gov/show/NCT00592332	Completed	Vanderbilt University	2007-06-30
NCT00592072	Effect of Medium Chain Fatty Acids on Cognitive Function During Acute Hypoglycemia in Patients With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT00592072	Completed	Yale University	2008-07-31
NCT00589589	Computer Decision Support to Achieve Glycemic Control in the ICU	https://ClinicalTrials.gov/show/NCT00589589	Completed	United States Army Institute of Surgical Research	2010-09-30
NCT00574639	Mechanisms of Hypoglycemia Associated Autonomic Dysfunction Question 2	https://ClinicalTrials.gov/show/NCT00574639	Completed	University of Maryland, Baltimore	2016-06-30
NCT00554281	Using Glucose Sensors to Prevent Hypoglycemia	https://ClinicalTrials.gov/show/NCT00554281	Completed	University of Alberta	2008-08-31
NCT00515801	Sulfonylurea Effects on Glucagon Regulation During Hypoglycemia in Type 1 DM	https://ClinicalTrials.gov/show/NCT00515801	Completed	University Hospital, Basel, Switzerland	NA
NCT00475345	Impact of Optimized Titration and Delivery of Bedtime Insulin on Prevention of Nocturnal Hypoglycemia	https://ClinicalTrials.gov/show/NCT00475345	Completed	McGill University	NA
NCT00467688	Effect of Continuous Glucose Monitoring on Course of Glucose in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT00467688	Completed	Forschungsinstitut der Diabetes Akademie Mergentheim	NA
NCT00453375	Phase 1 Study of BHT-3021 in Subjects With Type 1 Diabetes Mellitus	https://ClinicalTrials.gov/show/NCT00453375	Completed	Bayhill Therapeutics	2011-05-31
NCT00446264	Islet Allotransplantation With Steroid Free Immunosuppression	https://ClinicalTrials.gov/show/NCT00446264	Completed	University Hospital, Lille	2007-10-31
NCT00434954	Effect of Exenatide Plus Metformin vs. Insulin Aspart Plus Metformin on Glycemic Control and Hypoglycemia in Patients With Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT00434954	Completed	AstraZeneca	2009-06-30
NCT00434772	Glucagon in the Treatment of Hypoglycemia in Newborn Infants of Diabetic Mothers	https://ClinicalTrials.gov/show/NCT00434772	Completed	Shaare Zedek Medical Center	2009-05-31
NCT00418288	The Effect of GLP-1 on Glucose Uptake in the Brain and Heart in Healthy Men During Hypoglycemia	https://ClinicalTrials.gov/show/NCT00418288	Completed	University of Aarhus	2007-10-31
NCT00390728	Insulin Glargine in Type I Diabetes Mellitus> Main Study “AT.LANTUS”: A Trial Comparing Lantus Algorithms to Achieve Normal Blood Glucose Targets in Subjects With Uncontrolled Blood Sugar. Sub-study: “HALT”(Hypoglycaemia Avoidance With Lantus Trial)	https://ClinicalTrials.gov/show/NCT00390728	Completed	Sanofi	2003-08-31
NCT00360984	Prevention of Severe Hypoglycemia in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT00360984	Completed	Newcastle University	NA
NCT00346996	Insulin Analogues and Severe Hypoglycaemia	https://ClinicalTrials.gov/show/NCT00346996	Completed	Steno Diabetes Center Copenhagen	2011-11-30
NCT00322660	Adrenaline Injections to Children Born at Elective CS	https://ClinicalTrials.gov/show/NCT00322660	Completed	Hvidovre University Hospital	NA
NCT00292578	NAET® Testing Devices in Detection of Hypersensitivity to Cane Sugar	https://ClinicalTrials.gov/show/NCT00292578	Completed	Nambudripad’s Allergy Research Foundation	NA
NCT00286624	Anti-Thymocyte Globulin, Cyclosporine, and RAD in Islet Transplantation	https://ClinicalTrials.gov/show/NCT00286624	Completed	University of Minnesota	2006-08-31
NCT00285233	Delayed Mycophenolate Mofetil in Single-Donor Islet Allotransplantation in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT00285233	Completed	University of Minnesota	2004-09-30
NCT00285194	hOKT3γ1 (Ala-Ala) Combined With Sirolimus and Delayed Tacrolimus in Type 1 Diabetic Islet Allograft Recipients	https://ClinicalTrials.gov/show/NCT00285194	Completed	University of Minnesota	2004-01-31
NCT00265473	MGA031, Sirolimus and Tacrolimus in Islet Transplantation	https://ClinicalTrials.gov/show/NCT00265473	Completed	University of Minnesota	2010-05-31
NCT00264641	The Impact of Renin-angiotensin System on Brain Activation During Hypoglycaemia in Healthy Men, a PET Study	https://ClinicalTrials.gov/show/NCT00264641	Completed	Hypoglycaemia Research Group	2008-02-29
NCT00160056	The Effect of Antecedent Hypoglycaemia on β2-adrenergic Sensitivity	https://ClinicalTrials.gov/show/NCT00160056	Completed	Radboud University	2009-04-30
NCT00006508	Disorders of Systemic Glucose Balance	https://ClinicalTrials.gov/show/NCT00006508	Completed	National Center for Research Resources (NCRR)	NA

Observational Studiess

#If less then 500 studies

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03246243	Quantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High Risk	https://ClinicalTrials.gov/show/NCT03246243	Recruiting	Boston Children’s Hospital	2021-12-18
NCT03150030	Hypoglycaemia and Cardiac Arrhythmias in Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT03150030	Enrolling by invitation	University Hospital, Gentofte, Copenhagen	2020-01-06
NCT03034798	Suspending Basal Insulin Levels for Exercise in Adults With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03034798	Completed	York University	2016-07-28
NCT04454827	Fear of Hypoglycemia in Children and Adolecents With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT04454827	Completed	University of Ljubljana, Faculty of Medicine	2019-08-31
NCT02898428	Continuous Glucose Monitoring in New Mothers With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT02898428	Completed	Steno Diabetes Center Copenhagen	2018-03-31
NCT02690168	Testing Glial Pathways to HAAF in Human Subjects Using Carbon 13 Magnetic Resonance Spectroscopy	https://ClinicalTrials.gov/show/NCT02690168	Completed	Pennington Biomedical Research Center	2017-03-27
NCT02666521	Hypoglycaemia in People With Type 2 Diabetes in Primary Care	https://ClinicalTrials.gov/show/NCT02666521	Completed	University of Leicester	2017-06-30
NCT02347553	Effect of Hypoglycaemia on Social Cognition and Cardiac Conduction	https://ClinicalTrials.gov/show/NCT02347553	Completed	University of Edinburgh	2015-07-31
NCT02341313	Point of Care Ketone Measurement in the Newborn	https://ClinicalTrials.gov/show/NCT02341313	Completed	Cambridge University Hospitals NHS Foundation Trust	2018-03-31
NCT02325193	“MiniMed 640G System” User Evaluation With the Question of Reducing the Rate of Hypoglycemia	https://ClinicalTrials.gov/show/NCT02325193	Completed	Kinderkrankenhaus auf der Bult	2016-03-31
NCT02230631	A Survey on Hypoglycaemia Among Insulin-treated Patients With Diabetes	https://ClinicalTrials.gov/show/NCT02230631	Completed	Novo Nordisk A/S	2015-03-31
NCT02228642	Hypoglycemia in Hospitalized Patients	https://ClinicalTrials.gov/show/NCT02228642	Completed	University of Pittsburgh	2015-12-31
NCT02068300	The Role of 1.5-anhydro-D-glucitol as Clinical Biomarkers of Hypoglycemia in Patients With Diabetes	https://ClinicalTrials.gov/show/NCT02068300	Completed	Seoul National University Hospital	2016-02-29
NCT02056249	Evaluation of the Effect of Hypoglycemia With PET and a Norepinephrine Transporter Ligand	https://ClinicalTrials.gov/show/NCT02056249	Completed	Yale University	2017-06-30
NCT01941238	Incidence of Hypoglycemia During Ramadan in Patients With Type1 Diabetes on Insulin Pump Versus Multi Dose Injection	https://ClinicalTrials.gov/show/NCT01941238	Completed	King Abdullah International Medical Research Center	2013-09-30
NCT01897363	Hypoglycemia in Prader-Willi Syndrome	https://ClinicalTrials.gov/show/NCT01897363	Completed	University of Florida	2014-08-31
NCT01852968	Hippocampal Metabolism and Function in Patients With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT01852968	Active, not recruiting	University of Minnesota	2020-12-31
NCT01696266	An International Survey on Hypoglycaemia Among Insulin-treated Patients With Diabetes	https://ClinicalTrials.gov/show/NCT01696266	Completed	Novo Nordisk A/S	2013-12-30
NCT01628341	French Observational Survey to Assess Hypoglycaemia in Insulin-treated Diabetic Patients	https://ClinicalTrials.gov/show/NCT01628341	Completed	Novo Nordisk A/S	2012-09-30
NCT01523405	A Non-Interventional Study To Evaluate Diabetes Related Quality Of Life, Frequency And Impact Of Hypoglycemia In T2DM	https://ClinicalTrials.gov/show/NCT01523405	Completed	AstraZeneca	2013-02-28
NCT04430582	Pilot Study - Cognition in Patients With Hypoglycemia, Without Diabetes	https://ClinicalTrials.gov/show/NCT04430582	Recruiting	Joslin Diabetes Center	2024-06-15
NCT04428866	Mechanisms of Post-Bariatric Hypoglycemia	https://ClinicalTrials.gov/show/NCT04428866	Recruiting	Joslin Diabetes Center	2023-01-31
NCT04311021	Current State of Impaired Awareness of Hypoglycaemia in People With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT04311021	Recruiting	Radboud University	2021-02-01
NCT04219514	Investigating Novel Predictions of Hypoglycemia Occurrence in Real-world Models	https://ClinicalTrials.gov/show/NCT04219514	Active, not recruiting	Western University, Canada	2021-04-30
NCT04085978	Effects of a Hypoglycemia Protocol With Glucose Gel on Neonatal Intensive Care Unit (NICU) Admission	https://ClinicalTrials.gov/show/NCT04085978	Enrolling by invitation	Mednax Center for Research, Education, Quality and Safety	2021-09-30
NCT04020445	Simplification of Complex Insulin Regimens With Preserving Good Glycemic Control in Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT04020445	Recruiting	Bekes County Central Hospital	2021-01-01
NCT04011683	Hypoglycaemia and Cardiac Arrhythmias in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT04011683	Recruiting	Steno Diabetes Center Copenhagen	2021-12-01
NCT03956173	Hypoglycemia and Cardiac Arrhythmias in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03956173	Active, not recruiting	Steno Diabetes Center Copenhagen	2021-12-31
NCT03839511	Use of a Hyperinsulinemic-hypyglycemic Clamp to Study Hypoglycemia: a Method Development Study	https://ClinicalTrials.gov/show/NCT03839511	Active, not recruiting	Pennington Biomedical Research Center	2019-12-16
NCT03725657	Correlation Between Exercise and Insulin Dose in a Camp for Pediatric Type 1 Patients	https://ClinicalTrials.gov/show/NCT03725657	Completed	University of Campania “Luigi Vanvitelli”	2019-09-18
NCT03656887	Screening for Hypoglycemia in an Institutionalized Elderly Diabetic Population.	https://ClinicalTrials.gov/show/NCT03656887	Recruiting	Centre Hospitalier Universitaire Dijon	2021-02-28
NCT03605979	Continuous Glucose Monitoring and Hypoglycemia Unawareness in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03605979	Completed	CHU de Reims	2013-02-01
NCT03529188	French Version of the Scales of Fear of Hypoglycaemia in Children With Type 1 Diabetes and Their Parents	https://ClinicalTrials.gov/show/NCT03529188	Recruiting	University Hospital, Brest	2020-09-09
NCT03482154	Malglycemia in the Pediatric Hematopoietic Stem Cell Transplant Population	https://ClinicalTrials.gov/show/NCT03482154	Completed	University of Colorado, Denver	2019-06-30
NCT03481530	Role of CGMS Usage in Predicting Risk for Hypoglycemia	https://ClinicalTrials.gov/show/NCT03481530	Recruiting	University of Minnesota	2025-09-30
NCT03435198	Biomarkers in Exhaled Breath of Glucose Fluctuation in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT03435198	Completed	East Tennessee State University	2018-08-30
NCT01237509	EEG Changes of type1 Diabetes During Sleep -Insulin Induced Hypoglycemia	https://ClinicalTrials.gov/show/NCT01237509	Completed	UNEEG Medical A/S	2010-02-28
NCT01116674	Pediatric Critical Illness Hyperglycemia and Glycemic Control Registry	https://ClinicalTrials.gov/show/NCT01116674	Completed	Indiana University	2013-12-31
NCT01043042	Identification of Inpatients at Risk for Poor Glycemic Control	https://ClinicalTrials.gov/show/NCT01043042	Completed	Vanderbilt University Medical Center	2014-09-30
NCT00998374	Comparison Between Pyloric Preserving and Non-Pyloric Preserving Bariatric Surgery With Glucose Challenge	https://ClinicalTrials.gov/show/NCT00998374	Completed	Medtronic - MITG	2013-01-31
NCT00937079	Whole Body 111In-exendin-4 Imaging Study in Insulinoma Patients	https://ClinicalTrials.gov/show/NCT00937079	Completed	University Hospital, Basel, Switzerland	2011-12-31
NCT00916838	Neurocognitive Impact of Hypoglycemia in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT00916838	Completed	Washington University School of Medicine	2006-03-31
NCT00907881	The OBSTACLE Hypoglycemia Study (MK-0000-158)	https://ClinicalTrials.gov/show/NCT00907881	Completed	Merck Sharp & Dohme Corp.	2010-05-31
NCT00826007	Associated Factors in Perioperative Hypoglycemia in Patients With Diabetes	https://ClinicalTrials.gov/show/NCT00826007	Completed	William Beaumont Hospitals	2011-07-31
NCT00001276	Diagnosing and Treating Low Blood Sugar Levels	https://ClinicalTrials.gov/show/NCT00001276	Recruiting	National Institutes of Health Clinical Center (CC)	NA
NCT00810420	EEG-Changes During Insulininduced Hypoglycemia in Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT00810420	Completed	UNEEG Medical A/S	2007-10-31
NCT00793741	Measurement of Glucose Metabolism in Humans Using Magnetic Resonance at 4 Tesla. Substudy: Hypoglycemia Unawareness	https://ClinicalTrials.gov/show/NCT00793741	Completed	University of Minnesota	2017-03-31
NCT00734669	Risk of Hypoglycemia in Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT00734669	Completed	University of Giessen	2016-01-31
NCT00662922	Consequences of Hypoglycemia on Intensive Care Unit (ICU) Patients	https://ClinicalTrials.gov/show/NCT00662922	Completed	University Hospital Muenster	2008-09-30
NCT00614094	Maternal Hypoglycemia and Placental Pathology	https://ClinicalTrials.gov/show/NCT00614094	Completed	Oklahoma State University Center for Health Sciences	2008-06-30
NCT00607139	Hormone Responses During Hypoglycemia and the Accuracy of Continuous Glucose Monitors	https://ClinicalTrials.gov/show/NCT00607139	Completed	Jaeb Center for Health Research	2007-04-30
NCT00580710	Investigation Into the Effects Upon Brain Response to Change in Cirucating Glose Levels in Diabetes Mellitus	https://ClinicalTrials.gov/show/NCT00580710	Active, not recruiting	Yale University	2020-08-31
NCT00575783	Impact of Hypoglycemia Unawareness on Brain Metabolism Cognition in T1DM	https://ClinicalTrials.gov/show/NCT00575783	Completed	Yale University	NA
NCT00542334	Prevalence of Nocturnal Hypoglycemia in Children on a Type 1 Diabetes (TID) Insulin Regimen Using a Continuous Glucose Monitoring System (CGMS)	https://ClinicalTrials.gov/show/NCT00542334	Completed	Children’s Hospital of Eastern Ontario	2009-06-30
NCT01176656	Hypoglycemia: Physician and Patient Perspectives	https://ClinicalTrials.gov/show/NCT01176656	Completed	AstraZeneca	2010-12-31
NCT00493935	Effect of the Fat Content of the Bedtime Snack on Overnight Hypoglycemia	https://ClinicalTrials.gov/show/NCT00493935	Completed	Jaeb Center for Health Research	NA
NCT00468364	Comparison of Insulin Glargine and NPH Insulin at Night and at Hypoglycemia in Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT00468364	Completed	University of Giessen	NA
NCT00435565	Severe Hypoglycemia in Pregnant Women With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT00435565	Completed	Rigshospitalet, Denmark	NA
NCT00373854	Study of How Low Blood Sugar Affects the Way Blood Vessels Work	https://ClinicalTrials.gov/show/NCT00373854	Completed	Ohio State University	2006-09-30
NCT00351234	Carnitine Levels and Carnitine Supplementation in Type I Diabetes	https://ClinicalTrials.gov/show/NCT00351234	Completed	Children’s Mercy Hospital Kansas City	NA
NCT00109434	Study to Determine the Relationship Between Exercise and Hypoglycemia in Children With Type 1 Diabetes	https://ClinicalTrials.gov/show/NCT00109434	Completed	Jaeb Center for Health Research	NA

Registries

#If less then 500 registries

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT04428723	Mechanisms of Hypoglycemia in Patients Without Diabetes	https://ClinicalTrials.gov/show/NCT04428723	Recruiting	Joslin Diabetes Center	2024-05-31